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- For the course project,
I studied biological pathway modeling and made a
literature survey on the deterministic frameworks used for
modeling and simulating the metabolic and signaling pathways.
- You can find my
term paper presentation here
- You can download my
term paper here
- The papers
referenced in my paper:
- Savageau,
M.A.: Biochemical systems analysis, I.
Some mathematical properties of the rate law for
component enzymatic reactions. J. Theor. Biol. 25, 365-9, 1969
- Savageau,
M.A.: Biochemical systems analysis,
II. The steady-state solutions for an n-pool system using a power-law
approximation. J. Theor. Biol. 25, 370-9, 1969
- Savageau,
M.A.: Biochemical systems analysis,
III. Dynamic solutions using a power law approximation. J. Theor. Biol.
26, 215-26,
1970
- Curto, R.,
E.O. Voit, A. Sorribas, and
M.Cascante: Mathematical models of purine metabolism in man. Math.
Biosci. 151,
1-49, 1998 [pdf]
- O.
Wolkenhauer, H. Kitano, and K.-H. Cho:
Systems Biology: Looking at opportunities and challenges in applying
systems
theory to molecular and cell biology. IEEE Control Systems Magazine,
vol. 23,
no. 4, pp. 38-48, August 2003
- Michaelis, L.
and M.L. Menten: Die Kinetik der
Invertinkung. Biochem. Zeitschrift 49,
333-69, 1913
- Savageau,
M.A.: Biochemical Systems Theory:
Operational differences among variant representations and their
significance.
J. Theor. Biol. 151, 509-30, 1991
- O.
Wolkenhauer, M. Ullah, W. Kolch, and K.-H.
Cho: Modeling and simulation of intracellular dynamics: Choosing an
appropriate
framework. Accepted for publication in IEEE Trans. on NanoBioscience,
2004 [pdf]
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