We are located in the Department of Ophthalmology and Visual Sciences at Case Western Reserve University. The laboratory is interested in understanding the mechanism of action of rhodopsin and other G protein-coupled receptors. We use modern biophysical approaches involving the atomic force microscope and fluorescence-based assays to address fundamental questions related to signaling.
Our primary affiliation is in the Department of Ophthalmology and Visual Sciences. We also have secondary affiliations in the Department of Biochemistry and Department of Pharmacology.
Please feel free to explore this site to see what we are all about. Click here to take a tour of our laboratory space.
We organized the 14th Annual GPCR Retreat on October 17-19, 2013. A recap of the meeting is published in ASPET's Pharmacologist (Pages 234-235). Congratulations to Allison for winning a poster prize!
The laboratory has been awarded a 5 year R01 by the National Institutes of Health.
Our laboratory is featured in inSIGHT.
Our single-molecule force spectroscopy approach to understand rhodopsin structure and function is featured in the annual report from Research to Prevent Blindness.