5-NITP selectively inhibits translesion DNA synthesis and can
be used as a therapeutic agent
Non-natural nucleotide analogs such as 5-nitroindolyl triphosphate acts as
Chain terminator against abasic DNA synthesis.
Substituted indoyl nucleosides and nucleotides exhibit cytoxicity against
certain cancer cell lines and could be developed into chemotherapeutic agents
to prevent as to treat cancer.
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