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BIOPOTENTIAL - ISSUE 17 12/22/2015


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Biomedical Engineering Departmental Seminar Series

Mondays 11:30 AM -12:20 PM
Wickenden 322

Departmental Seminars are Completed for Fall 2015- Check back later for the schedule for Spring 2016

Biomaterials & Tissue Engineering Seminars

"The Happiest Hour of the Week"

Fridays 12:30-1:30
Wickenden 307

Biomaterials Seminars are Completed for Fall 2015- Check back later for the schedule for Spring 2016

Neuroengineering Seminars

"The Nerdiest Hour of the Week"

Fridays 9:00-10:15AM
Nord 400

NEC Seminars are Completed for Fall 2015- Check back later for the schedule for Spring 2016)

Imaging Seminars

"The Best Hour of the Week"

Tuesdays 11:30-12:20
Nord 410

Imaging Seminars are Completed for Fall 2015- Check back later for the schedule for Spring 2016


The BIOPOTENTIAL is the official newsletter of the BME Graduate Student Association. Each issue is digitally distributed (and updated online) on the Monday following the monthly GSA meeting, which all students, faculty, and associated researchers are encouraged to attend. For questions, comments, and concerns, feel free to contact GSA president, Rajat Shivacharan


Archives of previous issues can be found here.

To get in touch with the editors, email Anisha Rastogi, or Aditya Girish

Best wishes to all during the holiday season! May you all have a happy and prosperous new year!

BME Holiday Party!

A few glimpses from a well-deserved celebration of our department on 12/11/15:

Department Happy Hour!

We had a great turnout on 11/20/15! Thank you to everyone who came.

Watch for email notifications for upcoming department events!

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GSA Meeting Recap

Announcements 11/13/15:

Exec Updates

Next General Body Meeting 2/5/16

President and VP:

  • BMES (Tampa, FL) – Thank you to everyone who helped!!
  • Midwest Speaker Exchange
  • Exchange in March/April with Purdue University
    • Requirements:
      • Senior Level Graduate Student (4th year +)
      • Will count as an outside oral talk (GEC Approved)
      • Opportunity to network with faculty for potential post-doc opportunities
    • Next Ford Lecture – March 2nd, 2016

      Got a brilliant idea? You can contact either Rajat Shivacharan or Christian Anderson.


    • We raised $192 for the Greater Cleveland Food Bank! Thank you to all those who donated
    • Church of the Convenant has Saturday morning tutoring weekly! Click here for more information.

    Questions? Comments? Ideas for Volunteering Events? Contact Anna Czapar.


    • Outdoor soccer in now over! Great season to everyone who played (and see you at indoor next semester).
    • Basketball season is ongoing. Still time to join before playoffs start!
    • Lots more sports coming up next semester (indoor soccer, volleyball, floor hockey and more!)

    Contact Ivana Cuberovic for more information.

    Graduate Education Council:

    • Meeting the Med School Stipend Level:
      • Unclear how the medical school is paying for it
      • Unable to increase stipends further at this time
    • Possible Writing course
      • Grant writing R21 preparation
    • Open house!
      • Planning starts soon! Will need volunteers!
    • Master’s Students finding labs:
      • Look at all options: BME, Cancer Center, CCF, Pharmacology : expand from primary faculty
      • Contact the professor directly – not the PhD students in the lab
      • Find a strategy to make yourself valuable
      • Ask to attend lab meetings Ask questions at these meetings
    • Remember that it isn’t required
      • Course work master’s is always an option

    Questions, comments, or concerns? Contact Elizabeth Doolittle.

    Graduate Student Council:

    • GSS events can be found at the GSS calendar http://case.edu/gss/calendar.html

    For questions, comments, or concerns contact the GSC Representative Tina Lo

    Masters Notes:

    • Plan A students can switch to coursework at any time (Plan B) Coursework Master’s doesn’t require a lab. Does have a project component. For those concerned with finding position in desired labs A department representative is willing to present to students on how to approach finding a lab.

    For questions, comments, or concerns contact Yiqiao

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    Creativity Corner

    To send in things for the next Creativity Corner, email Anisha Rastogi or Aditya Girish

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    From PubMed (bolded authors indicate CWRU BME affiliation)

    1.Fredette EK, MacDonald DW, Underwood RJ, Chen AF, Mont MA, Lee GC, Klein GR, Rimnac CM, Kurtz SM. Does Metal Transfer Differ on Retrieved Ceramic and CoCr Femoral HeadsBiomed Res Int. 2015;2015:283038. doi: 10.1155/2015/283038. Epub 2015 Oct 25. PubMed PMID: 26583097.

    2. Uhde-Holzem K, McBurney M, Tiu BD, Advincula RC, Fischer R, Commandeur U, Steinmetz NF. Gd(3+)-Production of Immunoabsorbent Nanoparticles by Displaying Single-Domain Protein A on Potato Virus X. Macromol Biosci. 2015 Oct 6. doi: 10.1002/mabi.201500280. [Epub ahead of print] PubMed PMID: 26440117.

    3.Islam A, Chapin K, Moore E, Ford J, Rimnac C, Akkus O. Gamma Radiation Sterilization Reduces the High-cycle Fatigue Life of Allograft Bone.Clin Orthop Relat Res. 2015 Oct 13. [Epub ahead of print] PubMed PMID: 26463571.

    4. Zhou Z, Mondjinou Y, Hyun SH, Kulkarni A, Lu ZR, Thompson DH.Gd(3+)-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic-2-hydroxypropyl-β-cyclodextrin/Pluronic Polyrotaxane as a Long Circulating High Relaxivity MRI Contrast Agent. ACS Appl Mater Interfaces. 2015 Oct 14;7(40):22272-6. doi: 10.1021/acsami.5b05393. Epub 2015 Sep 29. PubMed PMID: 26417911.

    5.Jagodnik KM, Blana D, van den Bogert AJ, Kirsch RF. An optimized proportional-derivative controller for the human upper extremity with gravity. Gait PostureJ Biomech. 2015 Oct 15;48(13):3701-9. doi: 10.1016/j.jbiomech.2015.08.016. Epub 2015 Aug 29.] PubMed PMID: 26358531.

    6. Huang Y, Cao J, Zhang Q, Lu ZR, Hua MQ, Zhang XY, Gao H.Chitosan oligosaccharide based Gd-DTPA complex as a potential bimodal magnetic resonance imaging contrast agen. Magn Reson Imaging. 2015 Oct 17. pii: S0730-725X(15)00228-3. doi: 10.1016/j.mri.2015.10.006. [Epub ahead of print] PubMed PMID: 26485295.

    7. Cullins MJ, Gill JP, McManus JM, Lu H, Shaw KM, Chiel HJ. Sensory Feedback Reduces Individuality by Increasing Variability within Subjects. Curr Biol. 2015 Oct 19;25(20):2672-6. doi: 10.1016/j.cub.2015.08.044. Epub 2015 Oct 1. PubMed PMID: 26441353.

    8.Kalhan SC, Gruca L, Marczewski S, Bennett C, Kummitha C. Whole body creatine and protein kinetics in healthy men and women: effects of creatine and amino acid supplementation. Amino Acids. 2015 Oct 19. [Epub ahead of print] PubMed PMID: 26480831.

    9. Shah C, Beall EB, Frankemolle AM, Penko A, Phillips MD, Lowe MJ, Alberts JL. Exercise Therapy for Parkinson's Disease: Pedaling Rate Is Related to Changes in Motor Connectivity. Brain Connect. 2015 Oct 20. [Epub ahead of print] PubMed PMID: 26414696.

    10. Beene LC, Traboulsi EI, Seven I, Ford MR, Roy AS, Butler RS, Dupps WJ Jr. Corneal Deformation Response and Ocular Geometry: A Noninvasive Diagnostic Strategy in Marfan Syndrome. Am J Ophthalmol. 2015 Oct 24. pii: S0002-9394(15)00597-8. doi: 10.1016/j.ajo.2015.09.027. [Epub ahead of print]PubMed PMID: 26432567.

    11. Young DJ, Cong P, Suster MA, Damaser M. Implantable wireless battery recharging system for bladder pressure chronic monitoring. Lab Chip. 2015 Oct 27;15(22):4338-47. doi: 10.1039/c5lc00821b PubMed PMID: 26419677.

    12. Solorio L, Exner AA. Effect of the Subcutaneous Environment on Phase-Sensitive In Situ-Forming Implant Drug Release, Degradation, and Microstructure. J Pharm Sci. 2015 Oct 27. doi: 10.1002/jps.24673. [Epub ahead of print]. PubMed PMID: 26419677.

    13. Sheffler LR, Chae J. Hemiparetic Gait.Phys Med Rehabil Clin N Am. 2015 Nov;26(4):611-23. doi: 10.1016/j.pmr.2015.06.006. Epub 2015 Aug 14. Review. PubMed PMID: 26522901.

    14. Fu MJ, Knutson JS, Chae J. Stroke Rehabilitation Using Virtual EnvironmentsPhys Med Rehabil Clin N Am. 2015 Nov;26(4):747-57. doi: 10.1016/j.pmr.2015.06.001. Epub 2015 Aug 1. Review Pubmed PMID: 26522910.

    15. Cunningham DA, Potter-Baker KA, Knutson JS, Sankarasubramanian V, Machado AG, Plow EB. Tailoring Brain Stimulation to the Nature of Rehabilitative Therapies in Stroke: A Conceptual Framework Based on their Unique Mechanisms of Recovery. Phys Med Rehabil Clin N Am. 2015 Nov;26(4):759-74. doi: 10.1016/j.pmr.2015.07.001. Epub 2015 Sep 9. Review. Pubmed PMID: 26522911.

    16. Jiang K, Li W, Li W, Jiao S, Castel L, Van Wagoner DR, Yu X. Rapid multislice T1 mapping of mouse myocardium: Application to quantification of manganese uptake in α-Dystrobrevin knockout mice.Magn Reson Med. 2015 Nov;74(5):1370-9. doi: 10.1002/mrm.25533. Epub 2014 Nov 18. Pubmed PMID: 25408542.

    17. Rezai-Rad M, Bova JF, Orooji M, Pepping J, Qureshi A, Del Piero F, Hayes D, Yao S.Evaluation of bone regeneration potential of dental follicle stem cells for treatment of craniofacial defects.Cytotherapy. 2015 Nov;17(11):1572-81. doi: 10.1016/j.jcyt.2015.07.013. Epub 2015 Sep 3. Pubmed PMID: 26342992.

    18. Shamir RR, Dolber T, Noecker AM, Walter BL, McIntyre CC. Machine Learning Approach to Optimizing Combined Stimulation and Medication Therapies for Parkinson's Disease. Brain Stimul. 2015 Nov-Dec;8(6):1025-32. doi: 10.1016/j.brs.2015.06.003. Epub 2015 Jun 15. Pubmed PMID: 26140956.

    19. Walia P, Miniaci A, Jones MH, Fening SD. Influence of Combined Hill-Sachs and Bony Bankart Defects on Range of Motion in Anterior Instability of the Shoulder in a Finite Element Model. Arthroscopy. 2015 Nov;31(11):2119-27. doi: 10.1016/j.arthro.2015.04.099. Epub 2015 Jul 2. Pubmed PMID: 26142052.

    20. Nguyen JK, Jorfi M, Buchanan KL, Park DJ, Foster EJ, Tyler DJ, Rowan SJ, Weder C, Capadona JR. Influence of resveratrol release on the tissue response to mechanically adaptive cortical implants.Acta Biomater. 2015 Nov 6. pii: S1742-7061(15)30178-1. doi: 10.1016/j.actbio.2015.11.001. [Epub ahead of print] Pubmed PMID: 26553391.

    21. Potter-Baker KA, Bonnett CE, Chabra P, Roelle S, Varnerin N, Cunningham DA, Sankarasubramanian V, Pundik S, Conforto AB, Machado A, Plow EB. A game of hide and seek: Is it possible to recruit more patients for NIBS studies in stroke? J Neurol Sci. 2015 Nov 15;358(1-2):472-4. doi: 10.1016/j.jns.2015.08.030. Epub 2015 Aug 21. Pubmed PMID: 26320611.

    22. Stukel JM, Goss M, Zhou H, Zhou W, Willits RK, Exner AA. Development of a High-Throughput Ultrasound Technique for the Analysis of Tissue Engineering Constructs. Ann Biomed Eng. 2015 Nov 17. [Epub ahead of print] Pubmed PMID: 26577255.

    23. Au L, Meisch JP, Das LM, Binko AM, Boxer RS, Wen AM, Steinmetz NF, Lu KQ. Suppression of Hyperactive Immune Responses Protects against Nitrogen Mustard Injury. J Invest Dermatol. 2015 Dec;135(12):2971-81. doi: 10.1038/jid.2015.322. Epub 2015 Aug 19. Pubmed PMID: 26288355.

    24. Tyler DJ. Neural interfaces for somatosensory feedback: bringing life to a prosthesis. Curr Opin Neurol. 2015 Dec;28(6):574-81. doi: 10.1097/WCO.0000000000000266. Pubmed PMID: 26544029.

    25. Unal M, Akkus O. Raman spectral classification of mineral- and collagen-bound water's associations to elastic and post-yield mechanical properties of cortical bone. Bone. 2015 Dec;81:315-26. doi: 10.1016/j.bone.2015.07.024. Epub 2015 Jul 26. Pubmed PMID: 26211992.

    26. Collin GB, Hubmacher D, Charette JR, Hicks WL, Stone L, Yu M, Naggert JK, Krebs MP, Peachey NS, Apte SS, Nishina PM. Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation. Hum Mol Genet. 2015 Dec 15;24(24):6958-74. doi: 10.1093/hmg/ddv399. Epub 2015 Sep 24. Pubmed PMID: 26405179.

    27. Jun Xua, Lei Xiang Guanhao Wang, Shridar Ganesan, Michael Feldman, Natalie NC Shih, Hannah Gilmore, Anant Madabhushi. Sparse Non-negative Matrix Factorization (SNMF) based color unmixing for breast histopathological image analysis.Comput Med Imaging Graph. 2015 Dec;46 Pt 1:20-9. doi: 10.1016/j.compmedimag.2015.04.002. Epub 2015 Apr 28. Pubmed PMID: 25958195.

    28. Alapan Y, Icoz K, Gurkan UA.. Micro- and nanodevices integrated with biomolecular probes.Biotechnol Adv. 2015 Dec;33(8):1727-43. doi: 10.1016/j.biotechadv.2015.09.001. Epub 2015 Sep 10. Pubmed PMID: 26363089.

    29. Qiu C, Shivacharan RS, Zhang M, Durand DM. Can Neural Activity Propagate by Endogenous Electrical Field? J Neurosci. 2015 Dec 2;35(48):15800-11. doi: 10.1523/JNEUROSCI.1045-15.2015. Pubmed PMID: 26631463.

    30. Huynh CT, Nguyen MK, Tonga GY, Longé L, Rotello VM, Alsberg E. Photocleavable Hydrogels for Light-Triggered siRNA Release. Adv Healthc Mater. 2015 Dec 7. doi: 10.1002/adhm.201500778. [Epub ahead of print] Pubmed PMID: 26639103.

    31. Unal M, Jung H, Akkus O. Novel Raman Spectroscopic Biomarkers Indicate that Post-Yield Damage Denatures Bone's Collagen. J Bone Miner Res. 2015 Dec 17. doi: 10.1002/jbmr.2768. [Epub ahead of print] Pubmed PMID: 26678707.

    32. Gujrati M, Vaidya A, Lu ZR. Multifunctional pH-Sensitive Amino Lipids for siRNA Delivery. Bioconjug Chem. 2015 Dec 17. [Epub ahead of print] Pubmed PMID: 26629982.

    33. Gao Y, Erokwu BO, DeSantis DA, Croniger CM, Schur RM, Lu L, Mariappuram J, Dell KM, Flask CA.Initial evaluation of hepatic T1 relaxation time as an imaging marker of liver disease associated with autosomal recessive polycystic kidney disease (ARPKD). NMR Biomed. 2016 Jan;29(1):84-9. doi: 10.1002/nbm.3442. Epub 2015 Nov 26. Pubmed PMID: 26608869 .

    34. Zhang M, Graor H, Yan L, Kim J. Identification of Melanoma-reactive CD4+ T-Cell Subsets From Human Melanoma Draining Lymph Nodes. J Immunother. 2016 Jan;39(1):15-26. doi: 10.1097/CJI.0000000000000103. Pubmed PMID: 26641258 .

    35. Bastijanic JM, Kligman FL, Marchant RE, Kottke-Marchant K. Dual biofunctional polymer modifications to address endothelialization and smooth muscle cell integration of ePTFE vascular grafts. J Biomed Mater Res A. 2016 Jan;104(1):71-81. doi: 10.1002/jbm.a.35541. Epub 2015 Aug 6. Pubmed PMID: 26177606 .

    36. Sivaraman B, Sylvester A, Ramamurthi A. Fibrinolytic PLGA nanoparticles for slow clot lysis within abdominal aortic aneurysms attenuate proteolytic loss of vascular elastic matrix. Mater Sci Eng C Mater Biol Appl. 2016 Feb 1;59:145-56. doi: 10.1016/j.msec.2015.09.056. Epub 2015 Sep 16. Pubmed PMID: 26652359 .

    37. Luna A, Pahwa S, Bonini C, Alcalá-Mata L, Wright KL, Gulani V. Multiparametric MR Imaging in Abdominal Malignancies. Magn Reson Imaging Clin N Am. 2016 Feb;24(1):157-86. doi: 10.1016/j.mric.2015.08.005. Review. Pubmed PMID: 26613880 .

    If your publication is not listed in PubMed, please let Anisha Rastogi or Aditya Girish know so that they can include it in the next issue. Apologies for any missed publications.

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